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New circuit discovered: Can control fear, anger and anxiety

A team of scientists at the Cold Spring Harbor Laboratory (CSHL) has invented a new circuit in the mouse brain which can control the emotions in a brain like fear, anger and anxiety. It has been discovered from the circuit that these feelings are found within a definite region inside the brain. The main purpose of this project is to unearth the cause behind anxiety disorder inside a brain. Associate Professor Bo Li said that fear anxiety and memory are located around the central amygdale controlled by the neurons.

New circuit discovered: Can control fear, anger and anxiety

Research has found that a cluster of neurons is responsible for controlling the stress and anxiety. These neurons form the paraventricular nucleus of the thalamus or PVT. Scientists carried on experiments to see that neurons from the PVT extend deep into the central amygdale. When this connection us interrupted for any external reasons, impaired fear takes place. The scientists further researched on the data extracted from people suffering from post-traumatic stress disorder (PTSD) to identify chemical messengers that might connect the two structures. A molecule called BDNF is found to be associated with anxiety disorders. Patients with anxiety disorders are found to have mutations in BDNF.

The results obtained from the study has provided mechanistic insight into a circuit which is able to control fear in the brain, and provides a target for the future treatment of anxiety disorders, said Li.

New circuit discovered: Can control fear, anger and anxiety - Last modify: January 22nd, 2015, Author: Anik
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Anik is a Software Engineer by profession. He loves to spend a lot of time testing and reviewing the latest gadgets and software. He likes all things tech and his passion for smartphones is only matched by his passion for Sci-Fi TV Series.

  • Rudi Zimmermann

    What an interesting research! Congratulations to the scientists! I hope it will work on humans soon.

  • rainbowruin

    This is a great discovery regarding psychology related sickness. I’m just hope that this method will be used to make traumatic people cured from their trauma. Cause even if there are psychiatrist, the victim still couldn’t be cured fully.

  • Hana’a

    It’s very important & great scientific discovery that can help many patient suffering PTSD or any anxiety disorder but It also can be very critical if it used out of contest.

  • NenadS

    I hope that this research will help in treatment of anxiety disorders, but I’m not sure that emotions should be treated as something mechanical that happens in brain. Emotions happen for psychological reasons, I think.

  • Lily-Ann

    What a great discovery, considering so many people with anger issues or anxiety just can’t seem to get over it. Technology has come far and I really hope this helps people with their feelings.